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Image Search Results
Journal: Cancers
Article Title: Lysyl-Oxidase Dependent Extracellular Matrix Stiffness in Hodgkin Lymphomas: Mechanical and Topographical Evidence
doi: 10.3390/cancers14010259
Figure Lengend Snippet: Digital pathology imaging and measurement of lymph node stroma in HL and NHL. Slides of hematoxilin-eosin (HE, representative cases in Panel ( A )) or Mallory trichrome staining (representative cases in Panel ( B )) from LN sections of patients with HL ( n = 11), FL1-2 ( n = 6), FL3A ( n = 8), DLBCL ( n = 6), compared with 9 LDN, were subjected to Digital Pathology Imaging. Panel ( C ). HE sections were analyzed with the Genie software (right images in Panel ( A )) and the percentage area of stromal compartment per slide was calculated, adjusted to total tissue area in the image analyzed. Data are expressed as a percentage of green pseudocolor (stromal) areas and are the mean ± SEM of the indicated number of cases for each histological type. * p < 0.05 vs. LDN, FL1-2 and FL3A. Panel ( D ): digital images of Mallory trichrome stained sections were analyzed with an automated image analysis algorithm for color deconvolution (right images in Panel ( B )) and collagen areas quantified by the Image Scope software. Data are expressed as percentage of blue (collagen) areas and are the mean ± SEM of the indicated number of cases for each histological type. * p < 0.005 vs. LDN, FL1-2 and FL3A.
Article Snippet: Layers of each virtual slide annotation were created manually, selecting the whole area, and analyzed with the automated
Techniques: Imaging, Staining, Software